Weight Loss with Semaglutide & Tirzepatide (GLP-1s)
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If repeated cycles of weight gain and weight loss have failed to deliver the results you want, you are not alone. Many men and women struggle to lose weight due to genetics, stubborn cravings, slow metabolism, or other underlying health factors. At Kalos Medical Spa in Fort Worth, we offer guided medical weight loss with semaglutide and tirzepatide injections (GLP-1 receptor agonists)—two of the most effective, FDA-approved weight loss medications available.
What are weight loss injections?
Semaglutide (Wegovy®, Ozempic®) and tirzepatide (Mounjaro®, Zepbound®) are injectable medications, originally FDA-approved to treat diabetes, that help jump-start weight loss and improve metabolic health. These treatments are highly effective for people who need more than just willpower to lose weight.
What is semaglutide?
Semaglutide mimics a hormone (GLP-1) that regulates hunger and blood sugar to help you feel full longer and to reduce food cravings.
What is tirzepatide?
Tirzepatide goes a step further by activating both GLP-1 and GIP receptors, which work together to control appetite and enhance fat burning.
How do these injections help with weight loss?
Semaglutide and tirzepatide weight loss injections work by targeting key metabolic functions that affect your weight:
- Reduces appetite – Feel full faster and stay satisfied longer.
- Regulates blood sugar – Help prevent energy crashes and sugar cravings.
- Boosts metabolism – Support your body’s ability to burn fat efficiently.
Semaglutide and tirzepatide weight loss injections can help patients lose up to 15-20% or more of their body weight.
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Why we stand behind semaglutide and tirzepatide weight loss injections
Our goal is to help our patients look and feel their best. We understand that excess weight can pose aesthetic and health concerns, which is why we are here to offer safe and effective medications that improve vital health markers and achieve significant weight loss. Offering weight loss injections with semaglutide and tirzepatide in-house is convenient for our patients and aligns with our comprehensive care model.
Dr. Kirby and our experienced team at Kalos Medical Spa have been working with GLP-1 weight loss patients for years. Many of Dr. Kirby’s plastic surgery patients take weight loss medication to help them achieve their goal weight safely before plastic surgery, and others come to see her for body contouring procedures after weight loss to help complete their journey by addressing excess skin.
At Kalos Medical Spa, we also offer non-surgical treatments that help tighten mild skin laxity and target pockets of fat left behind once those last few pounds are gone. Coolsculpting may be an excellent solution to eliminate fat bulges in those genetically stubborn areas—even the ones you had in your youth.
Choosing our Fort Worth medical spa for your weight loss injections ensures you receive medically supervised treatments and access to surgical and non-surgical procedures to complete your transformation.
“Dr. Kirby, Carolyn, and staff are amazing! Their new office is a little oasis and I can’t say enough great things about my experiences at Kirby Plastic Surgery and Kalos Medical Spa! They always make you feel at home and comfortable asking questions and I’ve gotten nothing but the best treatment and results! Would give more stars if I could!”
—5-star Google Review
Are weight loss injections right for you?
You may be a good candidate for semaglutide or tirzepatide weight loss injections if:
- You have a BMI of 27 or higher and struggle with weight-related health issues.
- Diet and exercise alone have not worked for you.
- You want a doctor-supervised approach to weight loss.
Not sure if they are the right fit? Schedule a consultation at our Fort Worth medical spa and we will help you decide.
What to expect during treatment
Step 1: Consultation & assessment for semaglutide or tirzepatide
Dr. Kirby and our team will review your health history, weight loss goals, and lifestyle to create a personalized plan with either semaglutide or tirzepatide.
Step 2: Weekly weight loss injections
Quick once-a-week injections gradually increase dosing over time to allow your body to comfortably adjust to semaglutide or tirzepatide.
Step 3: Ongoing support & monitoring while taking semaglutide or tirzepatide
We will track your progress, guide you in managing any temporary side effects, and adjust your plan to ensure you stay on track for optimal weight loss.
“Kalos has top notch customer service and incredible providers. Carolyn PA-C listened intently to my needs, took her time, and my expectations were surpassed! I’ve been a patient here since 2017 and I am always impressed with how elevated the experience is from beginning to end. Thank you Dr. Kirby and team!”
—5-star Google Review
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Semaglutide vs. Tirzepatide: Which one is better?
Semaglutide and Tirzepatide are both effective for weight loss, but they work in slightly different ways.
Key differences
Appetite control
- Both medications reduce hunger, but tirzepatide is more potent in suppressing cravings.
Fat burning & metabolism
- Semaglutide boosts fat burning.
- Tirzepatide enhances fat burning and insulin sensitivity, making it more effective for weight loss in the right patient.
Expected weight loss
- Patients using semaglutide lose an average of about 15% of their body weight.
- Patients using tirzepatide lose an average of 20% of their body weight.
Which weight loss medication is right for you?
Semaglutide may be better if you:
- Need moderate weight loss and strong appetite control
Tirzepatide may be better if you:
- Want faster and more dramatic weight loss
- Need extra help managing insulin resistance or metabolic issues
We will help you determine if semaglutide or tirzepatide is best for you and your weight loss goal!
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Frequently Asked Questions
Are there any side effects when taking semaglutide for weight loss?
Some patients experience mild side effects when starting semaglutide. The most common side effects include:
- Nausea (especially in the first few weeks)
- Heartburn
- Bloating or gas
- Mild stomach discomfort
- Fatigue
- Occasional constipation or diarrhea
- Muscle loss
These symptoms are usually temporary and improve as your body gets used to the medication. We start each patient out with a low dose and gradually increase it to minimize side effects. We also recommend diet modifications when taking semaglutide for weight loss. Our professionals will discuss strategies to build or maintain muscle while losing weight to avoid muscle loss.
What about side effects when taking tirzepatide for weight loss?
Tirzepatide has a similar side effect profile to semaglutide. Common side effects include:
- Nausea and indigestion
- Mild stomach pain or bloating
- Constipation or diarrhea
- Fatigue or mild dizziness
Some people tolerate tirzepatide better than semaglutide, while others experience stronger nausea at the beginning. Like semaglutide, starting with a low dose and gradually increasing it helps minimize side effects when taking tirzepatide for weight loss.
How long does it take to see results with semaglutide?
Most patients start noticing changes within 4 weeks of using semaglutide. These initial results are often related to appetite control—patients report feeling full faster and experiencing fewer cravings within the first few weeks.
Weight loss progress varies, but studies show:
- By 3 months many patients lose 5-10% of their body weight
- By 6 months weight loss can reach 10-15% or more, depending on the dosage and diet and exercise habits
Patients who stick to a healthy, balanced diet and stay active while on semaglutide see faster, stronger weight loss results.
How long does it take to see results with Tirzepatide?
Tirzepatide often works faster than semaglutide, with many patients experiencing noticeable appetite suppression within the first 2-4 weeks.
On average, patients experience:
- 5-10% weight loss within the first 8-12 weeks
- 15-20% weight loss within 6-12 months
Since Tirzepatide activates both GLP-1 and GIP receptors, it helps the body process sugar more efficiently and burn more fat.
Can I stop GLP-1 injections once I reach my goal weight?
Once you reach your goal weight, you may be able to reduce or stop treatment, but this should be decided with medical supervision. Weight loss injections help regulate hunger hormones, so stopping abruptly could lead to a return of cravings and potential weight gain.
To maintain results, we recommend:
- Gradually tapering off the medication instead of stopping suddenly
- Focusing on long-term lifestyle changes (nutritious eating, regular exercise)
- Consider a maintenance dose, if needed, to keep cravings under control
We will work with you to develop a sustainable weight maintenance plan when you are ready.
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Do I need to follow a specific diet while taking weight loss medication?
While there is no specific diet required, making smart food choices will help maximize results. Many patients find that taking GLP-1 medications allows them to form new healthy habits that they plan to maintain long-term.
- Prioritize protein to help keep you full and support muscle mass.
- Eat fiber-rich foods to aid digestion and reduce bloating.
- Avoid processed carbs & sugary snacks to prevent blood sugar spikes and cravings.
- Stay hydrated to help with digestion and reduce nausea.
- Eat smaller, balanced meals as large portions can feel heavy when taking these medications.
Most patients naturally eat smaller portions due to reduced appetite, so it is very important that what you do eat is nutrient-dense to ensure your body gets the energy and nutrition you need to thrive.
How much does semaglutide cost?
The cost of semaglutide in Fort Worth depends on how you take the medication. We provide a customized monthly pricing estimate during your consultation.
How much does tirzepatide cost?
Weight loss injections with Tirzepatide in Fort Worth cost more than semaglutide and the total price of your treatment will also depend on your treatment duration. Our team provides cost estimates for both medications in our office.
Why choose Kalos Medical Spa in Fort Worth for weight loss injections?
Physician oversight is critical to your safety and success when taking semaglutide or tirzepatide for weight loss. Many weight loss clinics simply prescribe the medication with loose weight monitoring, but at Kalos Medical Spa, we take a comprehensive, patient-first approach:
- Guidance from trusted specialists. We work closely with you and check in regularly to fine-tune dosages for safe, comfortable, and sustainable weight loss.
- Personalized treatment plans. We believe in listening to our patients and providing a personalized weight loss plan. Your plan is customized based on your health, lifestyle, and long-term goals.
- Ongoing support & monitoring. Weight loss is a journey, and we are with you every step of the way. We are always available to help you manage side effects and guide you on how to maximize your weight loss and keep the weight from returning once you stop treatments.
- Science-backed, patient-centered care. We use the latest research and medical insights to help you lose weight safely and effectively while maintaining overall well-being.
Board-Certified Plastic Surgeon Dr. Emily Kirby is our on-site physician who oversees all treatments at Kalos Medical Spa, including weight loss medications. Dr. Kirby’s supervision means that each treatment plan is optimized for minimal side effects and maximum results and that your medication is sourced from reputable pharmacies for your safety.
- Key Benefits
- Glossary
FDA-approved for weight loss
Reduces hunger cues to help you avoid over-eating
Helps you feel full, not deprived
- Semaglutide: A prescription medication that helps control blood sugar and support weight loss by mimicking a natural hormone that regulates hunger.
- Diabetes: A condition where the body struggles to regulate blood sugar, often requiring medication to help maintain healthy levels.
- Ozempic®: A brand-name version of semaglutide used primarily to manage type 2 diabetes while also helping with weight loss.
- Wegovy®: A higher-dose version of semaglutide specifically approved for long-term weight loss in people with obesity.
- Insulin: A hormone that helps move sugar from the blood into cells for energy.
- Obesity: A medical condition in which excess body fat increases health risks; semaglutide or tirzepatide may help by reducing appetite and supporting weight loss.
- Low blood sugar: A condition where blood sugar drops too much.
- High blood sugar: When there is too much sugar in the bloodstream.
- Active ingredient: The main chemical in a medication responsible for its effects—semaglutide or tirzepatide is the active ingredient in weight loss medications.
- Glucagon-like peptide-1 (GLP-1): A hormone that regulates hunger and blood sugar.
- Clinical trials: Research studies that test how well a medication works and its safety before it receives FDA-approval or becomes widely available.
- Heart disease: A range of conditions affecting the heart; maintaining a healthy weight and blood sugar levels with medications like semaglutide or tirzepatide may reduce risks.
- Body mass index (BMI): A number calculated from weight and height to determine if a person is underweight, at a healthy weight, overweight, or obese.
- Liraglutide: A GLP-1 medication similar to semaglutide, used for weight loss and diabetes under brand names like Saxenda® and Victoza®.
- Diabetes-related complications: Long-term health problems caused by uncontrolled diabetes, including nerve damage, kidney disease, and heart issues.
- Tirzepatide: A newer medication that works like semaglutide but activates two receptors instead of one.
- Glucagon: A hormone that raises blood sugar levels, working opposite to insulin; sometimes used to treat dangerously low blood sugar.
- Gluconeogenesis: The body’s process of making glucose (sugar) from sources other than carbohydrates, like protein or fat, which helps maintain energy levels.
- Diabetic: A person with diabetes.
- GLP-1: Short for glucagon-like peptide-1, a natural hormone that helps control appetite and blood sugar.
- Retatrutide: Dubbed the “triple G” drug, works by mimicking three hunger-regulating hormones: GLP-1, GIP and glucagon. That appears to have more potent effects on a person’s appetite and satisfaction with food than other treatments. Expected FDA approval for weight loss in the USA soon.
References »
FDA approval label for semaglutide
FDA approval label for tirzepatide
Müller TD, Finan B, Bloom SR, D’Alessio D, Drucker DJ, Flatt PR, Fritsche A, Gribble F, Grill HJ, Habener JF, Holst JJ, Langhans W, Meier JJ, Nauck MA, Perez-Tilve D, Pocai A, Reimann F, Sandoval DA, Schwartz TW, Seeley RJ, Stemmer K, Tang-Christensen M, Woods SC, DiMarchi RD, Tschöp MH. Glucagon-like peptide 1 (GLP-1). Molecular Metabolism. 2019 Dec;30:72-130. doi: 10.1016/j.molmet.2019.09.010.
Wilcox G. Insulin and insulin resistance. The Clinical Biochemist Reviews. 2005 May;26(2):19-39. PMID: 16278749; PMCID: PMC1204764.
Wilding JPH, Batterham RL, Calanna S, Davies M, Van Gaal LF, Lingvay I, McGowan BM, Rosenstock J, Tran MTD, Wadden TA, Wharton S, Yokote K, Zeuthen N, Kushner RF; STEP 1 Study Group. Once-Weekly Semaglutide in Adults with Overweight or Obesity. The New England Journal of Medicine. 2021 Mar 18;384(11):989-1002. doi: 10.1056/NEJMoa2032183.
Your weight loss journey with semaglutide or tirzepatide begins at Kalos Medical Spa in Fort Worth
If you feel like you have tried it all and still cannot lose the weight, we are here for you. Call or text 817-292-4200 to book your consultation and let us help you create a realistic, science-backed weight loss plan that works for you.